几种小动物活体可见光成像系统的比较

小动物活体可见光成像系统由、暗箱、气体麻醉系统和操作分析软件组成。利用生物发光或荧光技术,在体内形成生物光源,利用灵敏的CCD拍摄成像,再通过分析软件对研究对象进行定位与测量,从而研究肿瘤的发生发展,基因的表达,药物作用机理以及蛋白质相互作用等。针对德国的Berthold(伯托)、美国的Caliper(Xenogen精诺真)、Kodak(柯达)、CRI和国产的中科恺盛几个常用机型,从几个方面总结出各自的特点。

Comparison of several kinds of small animals living visible light imaging system

The small animals in vivo optical imaging system comprises CCD, camera obscura, gas of anesthesia system and operating analysis software .The sensitive CCD in camera obscura can be taken into biological source obtained by bioluminescent or fluorescence technology in the body, and the analysis software can position and measure of object of study. Thereby, we could research the onset and progression of tumor, the expression of genes, the mechanism of drug action and protein interaction etc. In this paper, we will summarize their features of several commonly used models from several aspects, including Berthold from Germany, and Caliper (Xenogen ), Kodak , CRI from the United States , and zhongke kaisheng from domestic.