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Retroviruses released from a human tumor xenograft in nude mice induce colony-stimulating factor (CSF) activity in human fibroblastic cells |
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| Authors: | T Okabe K Hirashima T Terasima B Shimizu N Ohsawa F Takaku |
| Institution: | (1) The 3rd Department of Internal Medicine, Faculty of Medicine, University of Tokyo, Hongo 7-3-1, Bunkyo-ku, 113 Tokyo, Japan;(2) The 1st Department of Internal Medicine, Saitama Medical College, Morohongo 38, 350-04 Iruma-gun, Saitama, Japan;(3) Division of Pathology and Physiology, National Institute of Radiological Sciences, Anagawa, 280 Chiba, Japan;(4) Department of Virology and Rickettsiology, National Institute of Health, Shinagawa, 141 Tokyo, Japan |
| Abstract: | Summary A human colony-stimulating factor (CSF)-producing tumor transplanted into athymic nude mice released retroviruses in vitro. The viruses induced CSF activity in human fibroblastic cell lines. |
| Keywords: | Fibroblastic cells human mice nude retrovirus colony-stimulating factor CSF-producing tumor tumor xenograft |
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