| 小型猪背部成对扩张皮瓣模型的可行性研究 |
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| 引用本文： | 李薇薇,刘志飞,乔群,王晓军,朱琳,曾昂,张海林,白明,冯锐.小型猪背部成对扩张皮瓣模型的可行性研究[J].实验动物科学,2010,27(3):25-28. |
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| 作者姓名： | 李薇薇 刘志飞 乔群 王晓军 朱琳 曾昂 张海林 白明 冯锐 |
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| 作者单位： | 北京协和医学院,北京协和医院整形外科,北京,100032 |
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| 摘 要： | 目的评估背部成对皮瓣扩张器埋置在活体小型猪实验动物模型中的可行性及安全性。方法共选用6只10～12kg重的广西巴马小型猪,每头猪分别在背部两侧共设计6个5cm×7cm100mL埋扩张器的手术区域,背部脊柱左侧术区埋置扩张器,脊柱右侧术区作为对照组。结果实验组扩张皮瓣与对照组皮瓣的皮瓣存活率相比,有显著性差异(P<0.05)。但扩张皮瓣之间的存活率相比,没有显著性差异(P>0.05)。结论背部成对皮瓣埋置扩张器在小型猪模型中皮瓣存活率稳定,减少了个体差异,是用于扩张皮瓣研究的合适模型。
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| 关 键 词： | 小型猪 成对皮瓣 皮瓣存活 扩张皮瓣 |
| 收稿时间： | 2010-06-28 |
Observation of Effect of Minipig Dorsal Paired Expanded Flap Model |
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| LI Wei-wei,LIU Zhi-fei,QIAO Qun,WANG Xiao-jun,ZHU Lin,ZENG Ang,ZHANG Hai-lin,BAI Ming,FENG Rui.Observation of Effect of Minipig Dorsal Paired Expanded Flap Model[J].Shiyan Dongwu Kexue,2010,27(3):25-28. |
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| Authors: | LI Wei-wei LIU Zhi-fei QIAO Qun WANG Xiao-jun ZHU Lin ZENG Ang ZHANG Hai-lin BAI Ming FENG Rui |
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| Institution: | (Department of Plastic and Cosmetic Surgery,Peking Union Medical College Hospital,Beijing 100032,China) |
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| Abstract: | Objective To observe the effect and safety of minipig dorsal paired expanded flap model. Methods 6 minipigs with weight 10 ～ 12 kg were chosen. And 6 symmetrical adjoining area （7 cm × 5 cm each） were drawn on the minipig＇s dorsum. Soft tissue expanders（100 mL） were buried in the left area,and the right area were control group. Results The survival rate in the expanded flap group was statistically different with the control group（P 0. 05）. The survival rate within the expanded flaps group was not statistically different （ P 0. 05）. Conclusion The minipig dorsal paired expanded flap model shows lower difference in expanded flap survival rate than control group. This is a suitable model for expanded flap survival research. |
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| Keywords: | Minipig Paired flap Flap survival Expanded flap |
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