The hydrolysis of some L-amino acid-p-nitranilides with the normal and pregnant's serum aminopeptidases |
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| Authors: | M. Rybák B. Rybáková M. Petáková |
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| Affiliation: | (1) Institute of Haematology and Blood Transfusion, Praha, (Czechoslovakia);(2) Post-graduate Medical Institute, Clinic of Gynaecology and Obstetrics, Praha, (Czechoslovakia) |
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| Abstract: | Summary From 4 serum aminopeptidases (2 of pregnant and 2 of nonpregnant women's sera), the placental lysosomal (mol. wt 320,000) splits Lys-NAp only. B-Cys-NAp is hydrolyzed from the both placental enzymes, i.e. lysosomal and microsomal (mol. wt 145.000) AP. Ala-NAp is split by both nonpregnant serum AP more readily than Leu-NAp. |
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