| 喜树果中喜树碱和羟基喜树碱的快速分离 |
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| 引用本文： | 戴汉松,王家文,王涛. 喜树果中喜树碱和羟基喜树碱的快速分离[J]. 中国西部科技, 2013, 0(5): 1-1,6 |
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| 作者姓名： | 戴汉松 王家文 王涛 |
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| 作者单位： | [1]四川师范大学化学与材料科学学院,四川成都610066 [2]成都雅洁恩斯科研有限公司,四川成都610041 [3]四川理工学院化学与制药工程学院,四川自贡643000 |
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| 基金项目： | [基金项目]四川省科技厅基础应用项目（项目编号：05JY029-038-1）. |
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| 摘 要： | 采用碱法提取喜树果中的有效成分，提取液经酸化，氯仿、乙酸乙酯分别萃取后，浓缩重结晶，柱层析等步骤得到高纯度的喜树碱和羟基喜树碱。实验表明，此法提取率高，得到的产品收率、纯度高，原料利用度高，生产周期短，设备简单。
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| 关 键 词： | 喜树果 喜树碱 10-羟基喜树碱 柱层析 分离 |
Rapid Separation of Camptothecin and Hydroxycamptothecin from the Fruit of Camptotheca Acuminate Decne |
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| DAI Han-song,WANG Jia-wen,WANG Tao. Rapid Separation of Camptothecin and Hydroxycamptothecin from the Fruit of Camptotheca Acuminate Decne[J]. Science and Technology of West China, 2013, 0(5): 1-1,6 |
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| Authors: | DAI Han-song WANG Jia-wen WANG Tao |
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| Affiliation: | 1.The School of Chemistry and Material, Sichuan Normal University,Chengdu, Sichuan 610066,China;2.Chengdu Arkian Scientific Research Ltd.Chengdu,Sichuan 610041,China;3.College of Chemistry and Pharmaceutical Engincering,Sichuan University of Science and Engineering,Zigong,Sichuan 643000,China) |
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| Abstract: | We introduced the rapid separation method of effective components from the fruit of camptotheca acuminate decne. Extraction and column chromatography were used to produce high concentration camptothecin and hydroxycamptothecin. The result showed that the method is effective and productive. |
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| Keywords: | Fruit of camptotheca acuminate decne Camptothecin Hydroxycamptoyhecin Column chromatography Separation |
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