Carcinogenic activation of benzo(a)pyrene by iodine and ferric chloride in the respiratory tract of Syrian golden hamsters |
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| Authors: | F. Stenbäck J. Rowland |
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| Affiliation: | (1) Department of Pathology, University of Oulu, Kajaanintie, 52 D SF Oulu 22, (Finland);(2) Eppley Institute for Research in Cancer, University of Nebraska Medical Center, 42nd and Dewey Ave., 68105 Omaha, Nebraska, USA |
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| Abstract: | Summary Benzo(a)pyrene (0.5 mg), in itself weakly carcinogenic, when given in combination with ferric chloride (0,16 mg) or iodine (0,2 mg), alone noncarcinogenic, induced a number of tumors of different parts of the respiratory tract of Syrian golden hamsters.Partially supported by Public Health Service contracts PHS 43-68-959 and NO1 CP33278 from the Division of Cancer Cause and Prevention. The authors wish to thank Mrs Virginia Ooten for her technical assistance. |
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