Effects of cycloheximide on protein synthesis in human lung tumors,regenerating rat liver and hepatomas |
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| Authors: | C Agostini F Muci |
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| Institution: | (1) Centro Studi Patologia cellulare del C.N.R., Istituto di Patologia Generale dell'Università di Milano, via Mangiagalli 31, I-20133 Milano, (Italy) |
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| Abstract: | Summary 10–4 M cycloheximide (CHM) inhibits leucine incorporation to about the same degree in slices of human lung tumors, rat hepatomas, regenerating livers and normal tissues. At 10–6 M, CHM has a more pronounced effect on tumor tissue and regenerating liver than on normal tissues. 10–8 M CHM stimulates protein synthesis in normal rat liver slices. |
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