The effect of clomiphene citrate and estradiol on body weight,vaginal cornification,and uterine weight after chronic treatment of ovarlectomized rats |
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Authors: | W L Poteat |
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Institution: | (1) Department of Anatomy, Bowman Gray School of Medicine, Winston Salem, North Carolina, USA;(2) Present address: Department of Anatomy, University of South Carolina School of Medicine, Columbia, South Carolina, USA |
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Abstract: | Summary Clomiphene reduced the body weight gain of ovariectomized rats to a much greater degree than extradiol did. Estradiol had a more pronounced effect on vaginal cornification and uterine weight than clomiphene did.Acknowledgment. The work was supported by USPHS Grant AM-08029-6 awarded to Dr W. J. Bo. The support and guidance of Dr Bo is gratefully acknowledged. The clomiphene citrate was generously supplied by the Wm. S. Merrell Co., and the estradiol by Ciba Pharmaceutical Co. |
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