| 氨基酸—琥珀酸依托泊甙盐的制备 |
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| 引用本文： | 赵元鸿,王京昆.氨基酸—琥珀酸依托泊甙盐的制备[J].云南大学学报(自然科学版),1999,21(4):324-326. |
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| 作者姓名： | 赵元鸿 王京昆 |
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| 作者单位： | 云南大学药物研究开发中心，云南省医药产品质量检测站 |
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| 基金项目： | 云南省应用基础研究基金,云南省教委基金 |
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| 摘 要： | 从依托泊甙出发合成得到琥珀酸依托泊甙，琥珀酸依托泊甙与氨基酸相结合形成复盐，从而得到依托泊甙的新水溶性抗肿瘤前体药物．化合物Ｃ，Ｄ１，Ｄ２，Ｄ３均为首次合成
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| 关 键 词： | 依托泊甙 氨基酸－琥珀酸依托泊甙盐 水溶性抗肿瘤药物 |
Preparation of Amino acid Etoposide Succinate |
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| ZHAO Yuan hong ,YANG Fu you ,WANG Jing kun ,LI Rui ying.Preparation of Amino acid Etoposide Succinate[J].Journal of Yunnan University(Natural Sciences),1999,21(4):324-326. |
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| Authors: | ZHAO Yuan hong YANG Fu you WANG Jing kun LI Rui ying |
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| Institution: | ZHAO Yuan hong 1,YANG Fu you 1,WANG Jing kun 2,LI Rui ying 1 |
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| Abstract: | Etoposide succinate was synthesized from etoposide.Furthermore,it with amina acid combined together salifying.Therefore,three new soluble antitumor agents of etoposide were acquired for the first time. |
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| Keywords: | etoposide amino acid etoposide succinate soluble antitumor agents |
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