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An alternative magnesium-based root canal disinfectant: Preliminary study of its effi cacy against Enterococcus faecalis and Candida albicans in vitro
Authors:Lin Zhu  Peng Wan  Jiaohong Duan  Lili Tan  Ke Yang
Affiliation:Institute of Metal Research, Chinese Academy of Science, Shenyang 110016, China;Institute of Metal Research, Chinese Academy of Science, Shenyang 110017, China;General Hospital of Shenyang Military Region, Shenyang 110840, China;Institute of Metal Research, Chinese Academy of Science, Shenyang 110017, China;Institute of Metal Research, Chinese Academy of Science, Shenyang 110018, China
Abstract:Organisms invading root canal systems result in serious pulpal and periapical disease. To eliminate microorganisms and restrain secondary infections, dental materials with antibacterial properties are urgently needed in endodontics. Magnesium is considered as a promising biodegradable and biocompatible implant material. However, there are barely researches about its application in endodontic therapy. This work investigated the in vitro ef fi cacy of magnesium powder against Enterococcus faecalis and Candida albicans compared with a common disinfectant, calcium hydroxide. With Calcium hydroxide served as a comparison it demonstrated the qualifi ed antibacterial and anti-fungus properties of Mg as root canal disinfectant due to its high alkalinity of degradation, and the antimicrobial efficacy enhanced with the decreasing powder size.
Keywords:Disinfectant   Magnesium   Antibacterial property   Enterococcus faecalis    Candida albicans
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