| 环渤海水域磺胺类药物的含量特征 |
| |
| 引用本文： | 叶赛,张奎文,姚子伟,马德毅.环渤海水域磺胺类药物的含量特征[J].大连海事大学学报(自然科学版),2007,33(2):71-74. |
| |
| 作者姓名： | 叶赛 张奎文 姚子伟 马德毅 |
| |
| 作者单位： | 大连海事大学环境科学与工程学院，国家海洋环境监测中心国家海洋局近岸海域生态环境重点实验室，国家海洋环境监测中心国家海洋局近岸海域生态环境重点实验室，国家海洋环境监测中心国家海洋局近岸海域生态环境重点实验室 辽宁大连116026，国家海洋环境监测中心国家海洋局近岸海域生态环境重点实验室，辽宁大连116023，辽宁大连116023，大连水产学院生命科学与技术学院，辽宁大连116023，辽宁大连116023，辽宁大连116023 |
| |
| 基金项目： | 国家自然科学基金资助项目(40576051) |
| |
| 摘 要： | 为确认环渤海水域中抗生素的污染情况,对渤海各主要河流入海处的磺胺类抗生素含量状况进行调查.采用高效液相色谱-串联质谱法对14种磺胺类药物进行分析,外标法定量.经检测得出磺胺类化合物的质量浓度∶磺胺醋酰(SAAM)为2.1~4.4 ng/L,磺胺嘧啶(SDZ)为5.7~12.9 ng/L,磺胺甲基异唑(SMZ)为3.6~13.0 ng/L,磺胺噻唑(STZ)为9.2~32.2 ng/L,磺胺甲噻唑(SMTZ)为5.3~6.2 ng/L,磺胺氯哒嗪(SCP)为2.2 ng/L,磺胺间二甲氧嘧啶(SDM)为2.7~2.9 ng/L.检测结果表明,城市生活污水排放是环渤海水域磺胺类污染物的主要来源,对环境微生态系统已造成严重影响.
|
| 关 键 词： | 环渤海水域 磺胺类药物 河流污染 高效液相色谱-串联质谱 |
| 文章编号： | 1006-7736（2007）02-0071-04 |
| 修稿时间： | 2007-04-18 |
Occurrence of sulfonamide pharmaceuticals in water column around Bohai sea |
| |
| YE Sai,ZHANG Kui-wen,YAO Zi-wei,MA De-yi.Occurrence of sulfonamide pharmaceuticals in water column around Bohai sea[J].Journal of Dalian Maritime University,2007,33(2):71-74. |
| |
| Authors: | YE Sai ZHANG Kui-wen YAO Zi-wei MA De-yi |
| |
| Institution: | 1. College of Environmental Science and Engineering, Dalian Maritime University, Dalian 116026, China; 2. Coastal Ecology Key Laboratory, National Marine Environmental Monitoring Center, Dalian 116023, China;3. School of Life Science and Technology, Dalian Fisheries University, Dalian 116023, China |
| |
| Abstract: | Samples from the surface water of the main rivers which flow into Bohai sea were investigated to determine the pollution level of antibiotics in water column around Bohai sea.The occurrence of fourteen sulfonamides drugs were studied using high performance liquid chromatography-electrospray ionization tandem mass spectrometry with multiple reaction monitoring(MRM).The concentrations of sulfonamide compounds were as follows,SAAM 2.1-4.4 ng/L,SDZ 5.7-12.9 ng/L,SMZ 3.6-13.0 ng/L,STZ 9.2-32.2 ng/L,SMTZ 5.3-6.2 ng/L, SDM 2.7-2.9 ng/L and SCP 2.2 ng/L.The result shows that municipal wastewater discharge is the most important source of sulfonamides in Bohai sea water column which may have serious effect on environmental microcosm. |
| |
| Keywords: | water column around Bohai sea sulfonamide pharmaceutical river pollution high performance liquid chromatography tandem mass spectrometry(HPLC-MS/MS) |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
