Technical note about simultaneous recording of oxygen partial pressure and neuronal activity in cat cortex

Summary A method is described for simultaneous measurements of pO₂ and action potentials with microelectrodes using prefabricated gold wires. The construction and measuring with such gold electrodes is easier than with traditionally used platinum electrodes. Single electrode recording is done with a specially adapted electronic circuit, allowing the separation of both signals (pO₂ and action potentials. A measurement in cat brain illustrates this procedure.