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The C-terminal tetrapeptide of cholecystokinin decreases hunger in rats
Authors:L Halmy  C Nyakas  Judit Walter
Institution:(1) 1st Department of Medicine, Korvin Otto Hospital, POB 23, Budapest, (Hungary);(2) Research Division, Postgraduate Medical School, Budapest, (Hungary)
Abstract:Summary Intraperitoneal injection of the C-terminal tetrapeptide amide of cholecystokinin (CCK) suppressed feeding behaviour and food intake in rats deprived of food for 12 h in a dose-dependent manner. The CCK-4 possesses a hunger suppressive property similar to the full molecule of CCK.
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