The C-terminal tetrapeptide of cholecystokinin decreases hunger in rats |
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Authors: | L Halmy C Nyakas Judit Walter |
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Institution: | (1) 1st Department of Medicine, Korvin Otto Hospital, POB 23, Budapest, (Hungary);(2) Research Division, Postgraduate Medical School, Budapest, (Hungary) |
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Abstract: | Summary Intraperitoneal injection of the C-terminal tetrapeptide amide of cholecystokinin (CCK) suppressed feeding behaviour and food intake in rats deprived of food for 12 h in a dose-dependent manner. The CCK-4 possesses a hunger suppressive property similar to the full molecule of CCK. |
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