Effect of chronic ethanol treatment on peroxisomal acyl-CoA oxidase activity and lipid peroxidation in rat liver and heart |
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| Authors: | L. F. Panchenko S. V. Pirozhkov S. V. Popova V. D. Antonenkov |
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| Affiliation: | (1) All-Union Research Center for Medico-biological Problems in the Prevention of Alcohol Abuse and Alcoholism, Kropotkinsky per. 23, 119034 Moscow, USSR |
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| Abstract: | Summary Chronic ethanol administration was shown to increase catalase and acyl-CoA oxidase activities in rat myocardium but did not alter the activity of liver peroxisomal enzymes. As a result of alcohol consumption a 2–3-fold increase in the level of lipid peroxidation was observed in the heart tissue while in the liver the induction was much less pronounced. |
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| Keywords: | Ethanol peroxisomes lipid peroxidation alcoholic cardiomyopathy rat liver rat heart |
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