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小远志总多糖的微波提取及抗肿瘤活性研究
引用本文:吴翚,周俊,宛瑜,史达清.小远志总多糖的微波提取及抗肿瘤活性研究[J].徐州师范大学学报(自然科学版),2004,22(3):52-54.
作者姓名:吴翚  周俊  宛瑜  史达清
作者单位:徐州师范大学,化学系,江苏,徐州,221116
基金项目:江苏省高校自然科学研究计划项目(JH03 038,03KJD150213),徐州师范大学学生科研基金资助项目(XSK2003014)
摘    要:将微波技术运用于水提醇沉法提取小远志多糖。脱蛋白后得到总多糖,得率为3.35%.总多糖经二乙氨基乙基纤维素(DEAE—52)柱层析。分离得到两种均一组分.对总多糖进行了抗S180癌细胞活性研究。结果表明小远志总多糖对S180癌细胞具有明显的抑制作用。

关 键 词:小远志多糖  微波提取  抗肿瘤活性  中药材  分离
文章编号:1007-6573(2004)03-0052-03
修稿时间:2004年4月27日

The Total Polysaccharide Extracted from Polygala sibirica L.,var,megalopha,Fr.by Microwave and the Study on Its Anti-tumor Activity
WU Hui,ZHOU Jun,WAN Yu,SHI Da-qing.The Total Polysaccharide Extracted from Polygala sibirica L.,var,megalopha,Fr.by Microwave and the Study on Its Anti-tumor Activity[J].Journal of Xuzhou Normal University(Natural Science Edition),2004,22(3):52-54.
Authors:WU Hui  ZHOU Jun  WAN Yu  SHI Da-qing
Abstract:The polysaccharide (AP0) was extracted from Polygala sibirica L.,var,megalopha,Fr.by microwave in water,sagged by alcohol,and then deproteinizated (yield 3.35%). Two homogenital components were obtained by column chromography using cellulose DEAE-52 as fixed phase. And the anti-S180 tumor activity of AP0 was measured,the result indicated that AP0 had an evident inhibition against S180.
Keywords:polysaccharide in Polygala sibirica L    var  megalopha  Fr    microwave extraction  anti-tumor activity
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