钙及钙调素研究进展（Ⅱ）

ADVANCES IN THE RESEARCH OF CALCIUM AND CALMODULIN(II)

The paper gave a systematic review on the research Survey of Calcium and Calmodulin. in the paper, by lenses. One can first study the lens and then proceed to study images formed by an interface, this is the reverse of what mast textbooks do. This analysis is simpi and suitable foi teaching the authors laid stress on the multifunctions of Calcium and Calmodulin,the importance of Calcium ion- cycling across plasma membranes, the relationship of Calmodulin and intracellulat messengers(including CAMP,phosphatidyiinositols,Calcium ions),the molecular basis of auto -regulating the balance of Calcium ion concentraion in cells by controlling the activity,the efficiency,and the sensibiligy to calcium ions of membrane-associated Calcium pumps. The writers concluded that:l)The combination of Calcium ions with Calmodulin is a prerequisite of Calmodulins carrying out their functions,-2)The Calmodulin as calcium receptors has extensive functions,which are involved in almost all physiological and biochemical processes of living organisms such as cell recognition^ cell communications, cell propagation and cell cycle ceil regulation of metablism,cellular sustained esponses to outside signals anddd neurotransmitters synthesizing and seceting etc.; (3)Caimoduiins play a central role in regulating cellular metabolism and functions, by which CAlmodulins can mediate the message of calcium ions and regulate many kids of metabolic regulators, for instance, hormones (i. e. animal hormones and phytohormones),. the second messengei sysytems and so on. Yhus, Calmodulins are the copmprehensive regulator of cell metabolism and cellular total responses; (4)With the ovpplications of new physical-chemical, analytical instruments, the prospect of this research area is widespread.