|
|||||
|
|
Conversion of mammalian cyclic GMP-dependent protein kinase into modulator-dependent protein kinase (type II) in vitro |
|
| Authors: | W N Kuo L P Liu C F Duggans K M Foggie M J McNeal K Perry |
| Abstract: | The spontaneous conversion of mammalian cyclic GMP-dependent protein kinase (G-PK) into modulator-dependent protein kinase (type II) (M-PKII) in the absence of cGMP or histone was observed in vitro. The findings, together with similarity in substrate protein specificity, suggest that M-PKII is the catalytic subunit of mammalian G-PK. |
| Keywords: | |