Animal pharmacology of oxapadol (MD 720111), a new non-narcotic analgesic |
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| Authors: | G Mocquet A Coston M Jalfre |
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| Institution: | (1) Unité de Neuropharmacologie, Centre de Recherche Delalande, 10 rue des Carrières, F-92500 Rueil-Malmaison, France |
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| Abstract: | Summary Oxapadol is a non-narcotic analgesic with an unusual chemical structure. It possesses analgesic activity in 4 species similar to that of other non-narcotic reference analgesics. It also shows antipyretic and antiinflammatory effects and in the analgesic dose range is devoid of undesirable neurological, gastro-intestinal and cardiovascular side-effects.Acknowledgments. We thank Mss M. Mazadier, R. Adam and M. Delhommeau for technical assistance, Dr R.D. Porsolt for help with the text and Ms M. Fiquémont for secretarial assistance. |
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