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Radiation protection of pronormoblasts and normoblasts by 2-mercaptopropionylglycine (MPG)
Authors:M R Saini  P Uma Devi
Institution:(1) Radiation Biology Laboratory, Department of Zoology, University of Rajasthan, 302004 Jaipur, (India)
Abstract:Summary The pronormoblasts and normoblasts in Swiss albino mice were found to be very sensitive to radiation and their percentage was reduced drastically after exposure to gamma-rays. The degree of damage increased with increase in radiation dose. MPG reduced the initial damage and brought about an early and fast recovery. It is concluded that the drug protects the stem cells and thereby reduces the depletion of the regenerating pool which causes a more efficient and accelerated recovery.
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