57例不规则抗体干扰ABO血型鉴定分析

通过研究干扰血型鉴定的不规则抗体的特异性及类型,为正确的进行血型鉴定提供实验参考依据。2013年7月至2014年7月对22 558例患者进行血型及不规则抗体筛查检测,对因不规则抗体干扰血型鉴定患者进行抗体鉴定,明确抗体特异性及类型,并选择与抗体对应抗原阴性的红细胞制备反定型细胞进行血型鉴定,以排除干扰明确血型。结果:发现57名患者因MNS、Rh、Lewis、Duffy、P血型系统产生的不规则抗体干扰血型鉴定,其中抗-M最多,共37例,占64.91%,其次为抗-E和抗-e相关抗体,均为5例,分别占8.77%;抗-Lea3例,占5.26%;Ig G与Ig M类混合抗体37例,单纯Ig G类抗体14例,单纯Ig M类抗体6例。研究结果表明,Ig M和Ig G类不规则抗体均可干扰血型鉴定,以Ig M类为主。

The Analysis of Irregular Antibodies Interfered with ABO Blood Group Identification about 57 Patients

Through research the specificity and types of irregular antibodies which interfered blood group, to provide the basis for the correct blood group identification. In July 2013 to July 2014, 22558 cases of patients with blood group and irregular antibody screening tests, for the patients who irregular antibody interference blood group identification should complete antibodies identification and definite antibody specificity and type, so determine blood group.57 patients were found that the MNS, Rh, Lewis, Duffy, P blood group systems produced the irregular antibody can interfered with blood group identification, including anti-M 37 cases, accounting for 64.91%, followed by related antibodies to anti-E 5 cases, accounting for 8.77%; IgG and IgM mixed antibodies 37 cases, only IgG 14 cases, 6 cases of pure IgM antibodies. Both the IgM and IgG irregular antibody can interfere with blood group identification, give priority to with IgM class.