| 壳聚糖的改性及抑菌性研究 |
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| 引用本文： | 宋玉民,常彩萍,达文燕,栾尼娜.壳聚糖的改性及抑菌性研究[J].西北师范大学学报,2010,46(3):71-74. |
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| 作者姓名： | 宋玉民 常彩萍 达文燕 栾尼娜 |
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| 作者单位： | 宋玉民,常彩萍,栾尼娜,SONG Yu-min,CHANG Cai-ping,LUAN Ni-na(西北师范大学化学化工学院,甘肃兰州,730070);达文燕,DA Wen-yan(西北师范大学生命科学学院,甘肃兰州,730070) |
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| 基金项目： | 甘肃省自然科学基金，甘肃省高分子材料重点实验室开放基金 |
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| 摘 要： | 在氮气保护下,以硝酸铈铵为氧化还原引发剂,冰乙酸为溶剂,通过壳聚糖(CS)与盐酸聚六亚甲基胍盐衍生物(PHGH)的接枝共聚反应,制备出了具有较好水溶性的CS/PHGH材料.采用红外光谱、元素分析对该材料进行了表征,并对其抑菌性实验进行了研究.结果表明,合成的水溶性CS/PHGH对真菌、革兰氏阳性菌与革兰氏阴性菌的抑制作用均优于壳聚糖,尤其对真菌的抑菌效果最灵敏,其最小抑菌浓度(MIC)为0.39 mg.mL-1,抑菌圈直径为21 mm.
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| 关 键 词： | 壳聚糖(CS) 盐酸聚六亚甲基胍(PHGH) 接枝共聚 抑菌性 |
Modification of chitosan and its antibacterial |
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| SONG Yu-min,CHANG Cai-ping,DA Wen-yan,LUAN Ni-na.Modification of chitosan and its antibacterial[J].Journal of Northwest Normal University Natural Science (Bimonthly),2010,46(3):71-74. |
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| Authors: | SONG Yu-min CHANG Cai-ping DA Wen-yan LUAN Ni-na |
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| Institution: | SONG Yu-min1,CHANG Cai-ping1,DA Wen-yan2,LUAN Ni-na1(1.College of Chemistry , Chemical Engineering,Northwest Normal University,Lanzhou 730070,Gansu,China,2.College of Life Science,Lanzhou,730070,China) |
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| Abstract: | Grafting guanidine polymer(PHGH) onto chitosan(CS) is conducted by free-radical polymerization using ceric ammonium nitrate as an initiator in the acetic acid solution under nitrogen atmosphere and the CS/PHGH of new material is produced.The FT-IR,element analysis of new material is tested.And the antibacterial of the new material is investigated.The results show that the antibacterial activity of CS/PHGH is better than that of CS for fungus,gram-positive bacteria and gram-negative bacteria,especially for f... |
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| Keywords: | chitosan(CS) polyhexamethylene guanidine hydrochloride(PHGH) graft copolymer antibacterial |
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