Immunosuppressive effect of a mouse placenta fraction on H-2 incompatible split heart allografts |
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| Authors: | S -E Svehag W Schilling |
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| Institution: | (1) Institute of Medical Microbiology, Odense University, J. B. Winslows Vej 19, DK-5000 Odense, (Denmark);(2) Present address: Department of Immunology, National Bacteriological Laboratory, S-105 21 Stockholm, Sweden |
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| Abstract: | Summary A soluble placenta fraction from mice (A.CA) mated with H-2 histoincompatible males (A/Sn) significantly prolonged the survival of heterotopic A/Sn heart transplants in A.CA recipients. No prolongation of A/Sn heart graft survival was obtained with the corresponding A.CA placenta fraction after A.CA × A.CA mating.The work was supported by the Danish Medical Research Council (Project No. 512-3088). |
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