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Recent advances in brown adipose tissue biology |
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| Authors: | Yanyan Shen Xiaomeng Liu Meng Dong Jun Lin Qianwei Zhao HyuekJong Lee Wanzhu Jin |
| Institution: | 1. University of Science and Technology of China, Hefei, 230026, China 2. Key Laboratory of Animal Ecology and Conservation Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China 3. The University of the Chinese Academy of Sciences, Beijing, 100049, China |
| Abstract: | In mammals, white adipose tissue (WAT) store energy, whereas brown adipose tissue (BAT) burns energy. As a thermogenic organ, BAT can help maintain body temperature during cold exposure. Owing to its important roles in energy metabolism and regulating triacylglycerol levels, BAT has received great attention in treating obesity and its related diseases. Recent studies have suggested that BAT may secrete factor(s)—batokines—to regulate whole-body energy metabolism. In this review, we summarize the recent advances in the formation and function of BAT, as well as molecules that regulate the activity of BAT and beige fat. |
| Keywords: | Brown adipose tissue Batokine Energy regulation Beige adipocyte Anti-obesity |
| 本文献已被 CNKI 维普 SpringerLink 等数据库收录！ | |