Structure specificity of some immunoadjuvant synthetic glycopeptides |
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| Authors: | K. Mašek M. Zaoral J. Ježek V. Krchňák |
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| Affiliation: | (1) Institute of Pharmacology, Czechoslovak Academy of Sciences, Albertov 4, 12000 Praha 2;(2) Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, Praha, Czechoslovakia |
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| Abstract: | Summary The immunoadjuvant activity of muramyl dipeptide seems to be critically dependent on the type of substitution of the  -carboxyl group of the D-isoglutamine residue. Moreover the nonapeptide L-Ala-D-isoGlu-L-Lys-D-Ala-(Gly)5-OME also shows a definite effect. |
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