Candletoxins A and B, 2 new aromatic esters of 12-deoxy-16-hydroxy-phorbol,from the irritant latex of Euphorbia poisonii Pax |
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Authors: | R J Schmidt F J Evans |
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Institution: | (1) Department of Pharmacognosy, The School of Pharmacy, University of London, 29-39 Brunswick Square, WC1N 1AX London, (England) |
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Abstract: | Summary 2 new aromatic esters of 12-deoxy-16-hydroxy-phorbol, known as candletoxins A and B, were isolated from the irritant latex of Euphorbia poisonii Pax. Compound A was identified as 12-deoxy-phorbol-13-O-phenylacetate-16-O- -methyl-butyrate-20-acetate, and compound B was the C-20 desacetyl analogue.Acknowledgments. F. J. E. is grateful to the Central Research Fund of the University of London for a travel grant to visit West Africa, and R.J.S. is indebted to the Science Research Council for a research studentship. |
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