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Effect of the growth-promoting alpha-globulin (GPAG) on in vitro incorporation of exogenous DNA into mammalian cells |
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| Authors: | J. Marec Jarmila Keprtová Věra Spurná Eva Minářová J. Michl |
| Affiliation: | (1) Institute of Biophysics, Czechoslovak Academy of Sciences Brno, 612 65 Brno 12, Czechoslovakia;(2) Institute of Physiology, Czechoslovak Academy of Sciences Praha, 142 Praha, 4, Kr!["ccaron"]("/content/t27676325771w23l/xlarge269.gif") , Czechoslovakia |
| Abstract: | Summary The uptake of exogenous3H-DNA by mammalian cells is increased in the presence of a specific serum protein complex — growth-promoting alpha-globulin (GPAG).3H-DNA is retained in the cell nucleus in a quantity 3 times higher than for control cultures without GPAG even after 47h of additional cultivation in the medium without3H-DNA. |
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