Identification of SLC39A4, a gene involved in acrodermatitis enteropathica |
| |
| Authors: | Küry Sébastien Dréno Brigitte Bézieau Stéphane Giraudet Stéphanie Kharfi Monia Kamoun Ridha Moisan Jean-Paul |
| |
| Affiliation: | Laboratoire d'Etude du Polymorphisme de l'ADN, Faculté de Médecine, 1 rue Gaston Veil, 44035 Nantes Cedex, France. skury@sante.univ-nantes.fr |
| |
| Abstract: | We have characterized the human gene SLC39A4, which encodes a protein with features characteristic of a ZIP zinc transporter. The chromosomal location and expression of SLC39A4, together with mutational analysis of eight families affected with acrodermatitis enteropathica, suggest that SLC39A4 is centrally involved in the pathogenesis of this condition. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
