Degradation of encephalitogenic protein in aerobic ascorbic acid solutions |
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| Authors: | F C Westall M Thompson A B Robinson |
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| Institution: | (1) The Salk Institute for Biological Studies, P.O. Box 1809, 92112 San Diego, California, USA;(2) Linus Pauling Institute of Science and Medicine, 94025 Menlo Park, California, USA;(3) Present address: Linus Pauling Institute of Science and Medicine, 94025 Menlo Park, California, USA |
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| Abstract: | Summary Aerobic ascorbic acid solutions are capable of extensively cleaving the peptide chain of the myelin basic protein. Cleavage occurred most readily with C-terminal to aspartic acid, serine, threonine, glutamic acid and leucine residues.This research was supported in part by the National Multiple Sclerosis Society, grant number RG928-A-1. |
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