The GTPase superfamily: conserved structure and molecular mechanism |
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Authors: | H R Bourne D A Sanders F McCormick |
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Institution: | Department of Pharmacology, University of California, San Francisco 94143-0450. |
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Abstract: | GTPases are conserved molecular switches, built according to a common structural design. Rapidly accruing knowledge of individual GTPases--crystal structures, biochemical properties, or results of molecular genetic experiments--support and generate hypotheses relating structure to function in other members of the diverse family of GTPases. |
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