Na*-independent binding of [3H] muscimol to a membrane fraction of the brains of normal and dwarf mice |
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| Authors: | V Varga F V DeFeudis L Ossola M Geffard P Mandel |
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| Institution: | (1) Faculté de Médecine, Centre de Neurochimie du C.N.R.S., et Institut de Chimie Biologique, F-67085 Strasbourg Cedex, (France);(2) Present address: Faculté de Médecine, 1, rue Camille Saint-Saëns, F-33000 Bordeaux, France |
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| Abstract: | Summary Although their body weights were decreased by about 77% and their brain weights by about 30%, high-affinity 3H] muscimol binding to a cerebral membrane fraction was not altered in hereditary pituitary dwarf mice. Marked changes in the level of pituitary growth-associated hormones do not appear to be associated with a change in cerebral GABA-receptors.Supported by a UNESCO/IBRO Fellowship. Permanent address: Semmelweis University Medical School, 1st Institute of Biochemistry, Budapest, Hungary. |
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