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NPY基因SNPs与鸡屠体性状的关联分析
引用本文:周卫东,杨菲菲,宋雪梅,姜俊芳,邵涛.NPY基因SNPs与鸡屠体性状的关联分析[J].东北师大学报(自然科学版),2009,41(4).
作者姓名:周卫东  杨菲菲  宋雪梅  姜俊芳  邵涛
作者单位:1. 浙江省农业科学院畜牧兽医研究所,浙江,杭州,310021
2. 浙江省农业科学院畜牧兽医研究所,浙江,杭州,310021;南京农业大学动物科技学院,江苏,南京,210095
3. 南京农业大学动物科技学院,江苏,南京,210095
基金项目:浙江省自然科学基金资助项目,浙江省重点农业科研项目,浙江省农业科学院博士启动项目 
摘    要:利用PCR-SSCP法对AA肉鸡、仙居鸡(兼用型)和罗曼蛋鸡神经肽Y(NPY)基因全序列进行了单核苷酸多态(SNPs)检测.在基因内含子2中发现了5个紧密连锁的碱基变异位点:T2623C,C2704T,T2776G,T2787C和A2821G,这5个位点以单倍型的方式在突变基因型个体中遗传;各品种间NPY 基因AA野生型、AB杂合型和BB突变型基因及基因型频率分布差异极显著(P<0.01);基因型对鸡腹脂率、腿肌率及肝重有显著影响,BB基因型个体的腹脂率、腿肌率显著高于AA型和AB型,AB型个体的肝重显著高于AA型和BB型.因此,NPY基因可能是影响鸡脂肪沉积和屠体性状的主效基因或与主效基因相连锁.

关 键 词:神经肽Y  单核苷酸多态  屠体性状  

Relationship between single nucleotide polymorphisms of neuropeptide Y and slaughter performances in domestic chicken
ZHOU Wei-dong,YANG Fei-fei,SONG Xue-mei,JIANG Jun-fang,SHAO Tao.Relationship between single nucleotide polymorphisms of neuropeptide Y and slaughter performances in domestic chicken[J].Journal of Northeast Normal University (Natural Science Edition),2009,41(4).
Authors:ZHOU Wei-dong  YANG Fei-fei  SONG Xue-mei  JIANG Jun-fang  SHAO Tao
Institution:ZHOU Wei-dong1,YANG Fei-fei1,2,SONG Xue-mei1,JIANG Jun-fang1,SHAO Tao2(1.Institute of Animal Husb,ry , Veterinary Science,Zhejiang Academy of Agricultural Sciences,Hangzhou 310021,China,2.College of Animal Science , Technology,Nanjing Agricultural University,Nanjing 210095,China)
Abstract:The single nucleotide polymorphisms(SNPs) of neuropeptide Y(NPY) in meat-(AA),dual use-(Xianju) and layer-type(Roman) chickens were detected using single-strand conformation polymorphism.Five mutations were found in intron 2 of NPY,which were T2623C,C2704T,T2776G,T2787C and A2821G,respectively.These SNPs were linked closely each other and played roles in individuals of mutant in the form of haplotype.The distribution of genotypic frequency of AA,AB and BB was significant different among the chicken types(P<...
Keywords:neuropeptide Y  single nucleotide polymorphisms  slaughter traits  chicken
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