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大小鼠微卫星和 SNP 遗传检测的研究进展
引用本文:孙芳园,王越甲,杨炜峰,车路平,卢胜明,王小珂.大小鼠微卫星和 SNP 遗传检测的研究进展[J].实验动物科学,2014,31(3):60-65.
作者姓名:孙芳园  王越甲  杨炜峰  车路平  卢胜明  王小珂
作者单位:北京维通利华实验动物技术有限公司,北京100107
基金项目:北京市科技计划课题《实验动物微生物及遗传检测体系的建立》课题资助(No.111100067311001))
摘    要:摘要: 随着分子生物学技术的迅速发展,微卫星与单核苷酸多态性( single nucleotide polymorphism,SNP ) 技术已成 为实验动物遗传检测的重要手段。微卫星与 SNP 作为一类新型的分子标记,相对于生化与免疫标记,具有快速和 准确等优点。本文就微卫星与 SNP 在大鼠、小鼠遗传检测方面应用的进展做一综述。

关 键 词:大鼠    小鼠    SNP    微卫星    遗传检测  

Advances of Microsatellite and Single Nucleotide Polymorphism Analysis for Genetic Monitoring in Mouse and Rat
SUN fang-yuan,WANG Yue-jia,YANG Wei-feng,CHE Lu-ping,LU Sheng-ming,WANG Xiao-ke.Advances of Microsatellite and Single Nucleotide Polymorphism Analysis for Genetic Monitoring in Mouse and Rat[J].Shiyan Dongwu Kexue,2014,31(3):60-65.
Authors:SUN fang-yuan  WANG Yue-jia  YANG Wei-feng  CHE Lu-ping  LU Sheng-ming  WANG Xiao-ke
Institution:1.Vital River Laboratory Animal Technology, Co., Ltd, Beijing 100107, China;)
Abstract:With the rapidly advances in molecular biology technology,microsatellite and SNP has become an important means of analysis for genetic monitoring of laboratory animals.Microsatellite and SNPS,as a kind of new molecular markers,has the accurate and fast advantages,compared with the biochemical and immune markers.In this paper,we will have a detailed development of microsatellite and SNP analysis for genetic monitoring of mouse and rat has been reviewed.
Keywords:mouse  rat  microsatellite  SNP  genetic monitoring
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