Antigenic activity of lobster (Homarus vulgaris) arginine kinase and its cyanogen bromide fragments]

The antigenic saturation of lobster arginine kinase (38 000 daltons) by its specific antibodies has been studied. It was found that seven antigenic binding sites are simultaneously reactive on the surface of the enzyme in the presence of a large excess of antibodies or of their Fab fragments. After cyanogen bromide cleavage, the antigenic reactivity is distributed on several fragments of various sizes.