Changes in intracellular pH and cell volume during the early phase of DMSO-induced differentiation of friend erythroleukemia cells |
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| Authors: | Z Ellis A Schaefer G Koch |
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| Institution: | (1) Abteilung Molekularbiologie, Universität Hamburg, Grindelallee 117 IV, D-2000 Hamburg 13, (Federal Republic of Germany);(2) Present address: School of Medicine, Indiana University, Medical Sciences Building, 635 Barnhill Drive, 46223 Indianapolis, Indiana, USA |
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| Abstract: | Summary Changes in intracellular pH and water volume were measured after treatment of Friend erythroleukemia cells with 1.5% DMSO. It was found that a continuous decrease in pHi occurred, beginning 1 h after induction and a decline in pHi of 0.18 was measured after 9 h. In addition a decline in cellular water volume, of 12% only 15 min after induction, and 23% after 9 h, was observed.11 December 1986Acknowlegments. This work was supported by the  Deutsche Forschungsgemeinschaft . |
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| Keywords: | Friend cells differentiation intracellular pH cell volume |
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