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Synchrotron radiation XRF microprobe investigation of elemental distribution in femoral head slice with osteoporosis
Authors:Zhang Yuanxun  Cheng Feng  Li Deyi  Wang Yinsong  Zhang Guilin  Xu Hongjie  Liao Wensheng  Tang Tingting  Huang Yuying  He Wei
Affiliation:(1) Shanghai Institute of Nuclear Research, Chinese Academy of Sciences, 201800 Shanghai, China;(2) Shanghai No. 9 People’s Hospital, University of Shanghai Second Medicine, 200011 Shanghai, China;(3) Institute of High Energy Physics, Chinese Academy of Sciences, 100039 Beijing, China
Abstract:This note deals with the scanning of femoral head slices from both normal and osteoporosis subjects using synchrotron radiation X-ray fluorescence (SRXRF) microprobe technique. The sample preparation and experimental apparatus are described in detail. The quantitative computerized tomography (QCT) of elemental distribution, such as Ca, P, K, Fe, Zn, Sr and Pb in bone slice tissue including cartilage, substantial compact and substantial spongy, is investigated. Combined with the correlation between P, K, Zn, Sr and Ca, the loss way of minerals and the physiological functions of some metal elements in bone are also discussed.
Keywords:synchrotron radiation  X-ray fluorescence microprobe  inorganic elements  osteoporosis
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