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Structure of the porcine thyrotropin receptor: a 200 kilodalton glycoprotein heterocomplex
Authors:M N Islam  N R Farid
Institution:(1) Thyroid Research Laboratory, Health Sciences Center, Memorial University of Newfoundland, A1B 3V6 St. John's, Newfoundland, Canada
Abstract:Summary We have determined that the porcine thyroidal TSH receptor is a glycoprotein heterotetramer composed of two Mr sim 35,000 (epsiv) covalently linked subunits which interact noncovalently with two copies of delta (Mr 66,000) chains.Acknowledgments. This work was supported by grants from the Medical Research Council of Canada.
Keywords:Thyrotropin receptor  glycoprotein  delta and gif" alt="delta" align="BASELINE" BORDER="0"> and epsiv subunits" target="_blank">gif" alt="epsiv" align="BASELINE" BORDER="0"> subunits  electrophoresis
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