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Distal axonopathy in streptozotocin diabetes in rats |
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| Authors: | S. Chokroverty D. Seiden P. Navidad R. Cody |
| Affiliation: | (1) The Neurology Service, VA Medical Center, POB 308, 07939 Lyons, New Jersey, USA;(2) Departments of Neurology, Anatomy and Environmental and Community Medicine, UMDNJ-Robert Wood Johnson Medical School, New Brunswick and Piscataway, New Jersey, USA |
| Abstract: | Summary We noted the earliest morphological changes in the motor endplates 8 weeks after the induction of streptozotocin diabetes in rats. Morphometric measurements showed reduced axonal areas of the lateral plantar and the sicatic nerves in the diabetic rats 28 but not 2 and 8 weeks after the experiment. These findings suggested distal axonopathy. |
| Keywords: | Streptozotocin rats diabetic distal axonopathy |
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