Identification of susceptibility genes loci associated with type 2 diabetes |
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| Authors: | Lifei Liu Jingjing Lei Haiyun Liu Qinjie Zou Yuhua Sun Yancheng Xu Huimin Bi Fengjiao Deng Xueling Shao Siyang Liu |
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| Institution: | 1.College of Life Sciences,Wuhan University,Wuhan,China;2.Department of Cellular Biology,The University of Georgia,Athens,USA;3.Zhongnan Hospital of Wuhan University,Wuhan,China;4.People Hospital of Wuhan University,Wuhan,China;5.Department of Pathology,Medical College of Georgia,Augusta,USA |
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| Abstract: | In this study, we selected 10 susceptible SNPs loci to investigate their contribution to susceptibility to type 2 diabetes in Han Chinese among Hubei population. We genotyped SNPs rs5219, rs1801282, rs1470579, rs1111875, rs1081661, rs7754840, rs4506565, rs13266634, rs4402960, and rs5643981 by using the method of polymerase chain reaction-ligase detection reaction (PCR-LDR). In a case-control study, we have genotyped the 10 candidate susceptibility SNP loci, and here, we reported that the SNP rs5219 in KCNJ1... |
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| Keywords: | type 2 diabetes susceptibility gene single nucleotide polymorphism polymerase chain reaction ligase detection reaction (PCR-LDR) |
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