Zur « Lipoidlöslichkeit » von Arzneimitteln |
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| Authors: | H. Hanke W. Klinger |
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| Affiliation: | (1) Institut für Pharmazie und Lebensmittelchemie und Institut für Pharmakologie der Friedrich-Schiller-Universität, Jena, DDR |
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| Abstract: | Summary The solubility of phenazon, 4-aminophenazon and aminophenazon in heptan, neatsfoot oil, lard, lecithin and chloroform was determined. The results demonstrate that the solubility in chloroform or heptan cannot be taken as a measure of the fat-solubility, and that the solubility of phenazon in lipids has to be taken into consideration in determining the so-called antipyrinspace as a measure of total body water. |
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