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The 5′ untranslated region of fruA mRNA in Myxococcus xanthus positively regulates the expression of its own gene
作者姓名:WU Qian & MAO Xiaohua Key Laboratory of Developmental Genes and Human Diseases  Ministry of Education  
作者单位:WU Qian & MAO Xiaohua Key Laboratory of Developmental Genes and Human Diseases,Ministry of Education,Department of Genetics and Developmental Biology,Southeast University School of Basic Medical Sciences,Nanjing 210009,China
摘    要:Studyingthemolecularmechanismsgoverningmorphogenesisofmulticellularstructureandcelldifferen-tiationhasbeenoneofthecentralthemesinlifesciences.M.xanthus,aGram-negativebacterium,isoneofthesim-plestorganismsthatundergoaprogramofmulticellulardevelopment.Inresponsetonutrientstarvation,approxi-mately100000cellsmovetowardanaggregationcentertoformafruitingbody.Withinthenascentfruitingbody,rod-shapedcellsgraduallyshortenanddifferentiateintoroundmyxospores.Sporesgerminatetoinitiatevegetativegrowthifnut…

关 键 词:Myxococcus  xanthus    fruA    5′-UTR    development    regula-tion.
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