| SARS病毒RNA二级结构及RNAi作用靶位的计算机预测 |
| |
| 引用本文： | 柳平英,刘志学,郭景康. SARS病毒RNA二级结构及RNAi作用靶位的计算机预测[J]. 上海大学学报(自然科学版), 2004, 10(4): 435-440 |
| |
| 作者姓名： | 柳平英 刘志学 郭景康 |
| |
| 作者单位： | 上海大学,理学院,上海,200436;上海大学,生命科学学院,上海,200436 |
| |
| 摘 要： | 该研究使用两个基于不同算法的RNA二级结构预测软件RNAstructure 3．71和RNAdraw V1．1b2，通过对SARS冠状病毒BJ01和TOR02株的基因组序列的二级结构进行计算机初步模拟，得到可能用于RNAi作用药物设计的6个结构．
|
| 关 键 词： | SARS冠状病毒 RNA二级结构 RNAi作用靶位 计算机预测 |
| 文章编号： | 1007-2861(2004)04-0435-06 |
| 修稿时间： | 2003-07-08 |
Computer Simulation of RNA Secondary Structures of SARS Virus and Prediction of Target Sites of RNAi Action |
| |
| LIU Ping-ying,LIU Zhi-xue,GUO Jing-kang. Computer Simulation of RNA Secondary Structures of SARS Virus and Prediction of Target Sites of RNAi Action[J]. Journal of Shanghai University(Natural Science), 2004, 10(4): 435-440 |
| |
| Authors: | LIU Ping-ying LIU Zhi-xue GUO Jing-kang |
| |
| Affiliation: | LIU Ping-ying~1,LIU Zhi-xue~2,GUO Jing-kang~1 |
| |
| Abstract: | In this research, the secondary structures of BJ01 and TOR02 isolates' SARS-Cov genome sequences are simulated with two software tools: RNAstructure 3.71 and RNAdrawV1.1b2, which are based on different algorithms to predict RNA secondary structures. Six potential structures have been obtained, which can be used in designing medicines by RNAi action. |
| |
| Keywords: | SARS-Cov RNA secondary structures RNAi acting targets computer prediction |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
