| SD大鼠凝血四项检查正常参考值范围探讨 |
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| 引用本文： | 刘珍清,赵媛媛,任一冉,张美龄,刘颖.SD大鼠凝血四项检查正常参考值范围探讨[J].实验动物科学,2021,38(3):59-61. |
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| 作者姓名： | 刘珍清 赵媛媛 任一冉 张美龄 刘颖 |
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| 摘 要： | 目的 建立北京中医药大学北京中医药研究院医学检验实验室SD大鼠血浆中凝血四项正常参考值范围.方法 利用全自动凝血分析仪测定40只SD大鼠血浆中的凝血酶原时间(PT)、活化部分凝血酶时间(APTT)、凝血酶时间(TT)和纤维蛋白原(FIB)水平.结果 正常SD大鼠血浆中的凝血四项参数比较稳定,PT的参考值范围为14.96...
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| 关 键 词： | SD大鼠 凝血四项 参考值 |
Reference Range of Four Tests of Coagulation in the Plasma of SD rats |
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| LIU Zhenqing,ZHAO Yuanyuan,REN Yiran,ZHANG Meiling,LIU Ying.Reference Range of Four Tests of Coagulation in the Plasma of SD rats[J].Shiyan Dongwu Kexue,2021,38(3):59-61. |
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| Authors: | LIU Zhenqing ZHAO Yuanyuan REN Yiran ZHANG Meiling LIU Ying |
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| Abstract: | Abstract: Objective To establish the reference range of four tests of coagulation in the plasma of SD rats in themedical laboratory of Beijing institute of Chinese medicine, Beijing university of Chinese medicine. MethodProthrombin time ( PT) , activated partial thrombin time ( APTT) , thrombin time ( TT) and fibrinogen ( FIB )levels in the plasma of forty SD rats were measured using automated coagulation analyzer. Result The referencerange of PT, APTT, TT and FIB was 14. 96 to 15. 86 s, 15. 25 to 18. 83 s, 43. 06 to 53. 18 s and 1. 94 to 2. 21 g /L with stable result, respectively. Conclusion The reference range of four parameters of coagulation in normal SDrats was established, which provides reference value for pharmacological experiments and is of great significance for the safety toxicological evaluation of SD rats. |
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