The effect of acidic polysaccharides and prostaglandin-like substances isolated fromPropionibacterium acnes on granulocyte chemotaxis |
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| Authors: | Belsheim J Dalen A Gnarpe H Hellgren L Iversen O -J Vincent J |
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| Institution: | (1) Department of Clinical Bacteriology, Gävle Hospital, Gävle, (Sweden);(2) Department of Microbiology and Department of Dermatology, University of Trondheim, Trondheim, (Norway) |
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| Abstract: | Summary Three acidic polysaccharide (AP) fractions and the prostaglandin-like substances (PLS) isolated fromP. acnes were investigated regarding their chemotactic activities on polymorphonuclear leukocytes. Both AP's and PLS induced a significant chemotactic response, which suggests their involvement in inflammatory acne vulgaris. |
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