Fetal calf serum alters cyclic adenosine 3',5'-monophosphate's effect on heme synthesis in vitro. |
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Authors: | C P Olander |
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Abstract: | An investigation of the effect of cAMP on heme synthesis of rat bone marrow cells revealed that at 10(-2) M this cyclic nucleotide inhibits heme synthesis and that optimum stimulation occurs at 10(-4) M. Some unidentified constituent of fetal calf serum in the culture medium modifies the direction and degree of cAMP's effect. |
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