| 拉米夫定治疗慢性乙型肝炎的研究进展 |
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| 引用本文： | 张秋蓉,顾伟.拉米夫定治疗慢性乙型肝炎的研究进展[J].大理学院学报,2005,4(3):85-87. |
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| 作者姓名： | 张秋蓉 顾伟 |
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| 作者单位： | 大理学院临床医学院内科学教研室,云南,大理,671000 |
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| 摘 要： | 目的:介绍拉米夫定治疗慢性乙型肝炎的进展概况。方法:查阅、分析、归纳有关文献。结果:拉米夫定能明显控制HBVDNA复制,血清谷丙转氨酶恢复正常,减少慢性乙型肝炎的反复复发。结论:拉米夫定是新一代核苷类抗乙肝病毒药物,可通过降低乙型肝炎病毒(HBV)依赖RNA的DNA多聚酶生物活性,明显抑制HBVDNA的合成,是治疗慢性乙型肝炎的新选择。
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| 关 键 词： | 拉米夫定 慢性乙型肝炎 进展 |
| 文章编号： | 1672-2345(2005)03-0085-03 |
| 修稿时间： | 2004年10月22 |
Research Advance on Chronic Hepatitis B with Lamivudine Therapy |
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| ZHANG Qiu-rong,GU Wei.Research Advance on Chronic Hepatitis B with Lamivudine Therapy[J].Journal of Dali University,2005,4(3):85-87. |
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| Authors: | ZHANG Qiu-rong GU Wei |
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| Abstract: | Objective: To introduce the research advances on chronic hepatitis B with lamivudine therapy. Methods: To study, analyses and sum up the relative literatures. Results: Lamivudine could effectively control HBV DNA replication, making ALT normal, it also could decrease the relapse rate of chronic hepatitis B. Conclusion: Lamivudine is a new kind of anti-hepatitis B agent from nucleosides. It inhibits the DNA synthesis of HBV via decreasing the bio-activity of DNA polymerase that depended on RNA. It may be useful in treatment of chronic hepatitis B. |
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| Keywords: | Lamivudine Chronic hepatitis B Advance |
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