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Effect of pylorus ligation on gastric mucosal mast cell population in normal and adrenalectomised albino rats
Authors:S S Sathiamoorthy  A K Ganguly  O P Bhatnagar
Institution:(1) Department of Physiology, Jawaharlal Institute of Postgraduate Medical Education and Research, 605006 Pondicherry, (India);(2) Department of Physiology, Maulana Azad Medical College, 110002 New Delhi, (India);(3) Department of Physiology, Government Medical College, Surat 1, (India)
Abstract:Summary Pylorus ligation in normal albino rats acts like a stressor leading to degranulation of mast cells in gastric mucosa, thereby decreasing their number. This decrease is less pronounced when pylorus ligation is done in adrenalectomized rats. This implies that action of a stressor on gastric function involves the adrenal steroids which liberate the powerful gastric stimulant histamine from gastric mucosal mast cells.
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