| 阿片类物质的外周镇痛作用 |
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| 引用本文： | 张文华,江剑平. 阿片类物质的外周镇痛作用[J]. 福建师范大学学报(自然科学版), 2011, 27(2): 144-147 |
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| 作者姓名： | 张文华 江剑平 |
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| 作者单位： | 福建师范大学生命科学学院,福建省发育和神经生物学重点实验室,福建,福州,350108 |
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| 基金项目： | 国家自然科学基金资助项目,福建省教育厅资助项目,福建师范大学优秀青年骨干教师培养基金资助项目 |
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| 摘 要： | 就外周阿片受体的分布和阿片类物质的外周镇痛作用及机制的相关研究进展进行综述.阿片类物质的镇痛作用通过中枢和外周两种机制,研究表明:阿片类物质的外周镇痛作用是通过外周阿片受体起作用的.初级感觉神经元内及其外周末梢上存在着各类阿片受体,在炎症及神经损伤的情况下,阿片受体合成增加并转运到神经末梢或者受损部位,增加传导痛觉冲动...
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| 关 键 词： | 外周镇痛 阿片受体 阿片类物质 |
The Peripheral Analgesic Effect of Opioids |
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| ZHANG Wen-hua,JIANG Jian-ping. The Peripheral Analgesic Effect of Opioids[J]. Journal of Fujian Teachers University(Natural Science), 2011, 27(2): 144-147 |
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| Authors: | ZHANG Wen-hua JIANG Jian-ping |
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| Affiliation: | ZHANG Wen-hua,JIANG Jian-ping(College of Life Sciences,Fujian Normal University,Fujian Key Laboratory of Developmental and Neuro Biology,Fuzhou 350108,China) |
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| Abstract: | The distribution of peripheral opioid receptors and aralgesic effect and mechanisms of peripheral opioid ewre summarized.Analgesic effect of opioids includes central and peripheral mechanisms.Potent and significant analgesic effects can be brought about by opioids acting outside the central nervous system.Primary sensory neurons and their peripheral nerve terminals express opioid receptors.In inflammation and nerve injury cases,opioid receptors synthesis may increase and be transported to the peripheral ner... |
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| Keywords: | peripheral analgesia opioid receptor opioids |
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