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Antibiotic sensitivity testing by flow microcalorimetry
Authors:A E Beezer  R J Miles  E J Shaw  P Willis
Institution:(1) Departments of Chemistry and Applied Biology, Chelsea College, University of London, Manresa Road, SW3 6LX London, England;(2) Department of Bacteriology, St. Bartholomew's Hospital Medical School, West Smithfield, London, England
Abstract:Summary The proposed flow microcalorimetric method for the diagnosis of bacteriuria has been extended to include antibiotic sensitivity testing. Sensitive organisms rapidly (4–8 min) show thermal responses to the added antibiotics over the normal range of concentrations (1×, 2×, MIC value).
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