Changes in gentamicin pharmacokinetics after reduction of renal parenchyma |
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Authors: | O. Schück J. Morávek M. Hatala |
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Affiliation: | (1) Institute for Clinical and Experimental Medicine, Bud jcvická 800, 14622 Prague 4-Kr , ( SSR) |
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Abstract: | Summary The relationship between the elimination constant of gentamicin and the percentage of functioning nephrons in rats cannot be characterized by a simple linear relation. The results support the assumption that gentamicin elimination per residual nephron increased. |
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