Impaired amylase release from the parotid gland of rats treated with reserpine |
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| Authors: | J R Martinez O H Petersen |
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| Institution: | (1) Department of Physiology, University of Dundee Medical School, DD1 4HN Dundee, Scotland;(2) Present address: Department of Child Health, University of Missouri School of Medicine, 65212 Columbia, Missouri, USA |
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| Abstract: | Summary Using an automated system for the analysis of amylase, the release of this enzyme was compared in superfused parotid gland segments from control and reserpine treated rats. Stimulant-evoked amylase release was delayed and of smaller magnitude in the glands of the treated animals and a reduction of the transmembrane K+ gradient caused a smaller and short lasting reduction in Ach-evoked release of amylase in the glands from these animals.This work was supported by grants from the Cystic Fibrosis Research Trust (U.K.), Cystic Fibrosis Foundation (USA) and University of Missouri. |
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